Dose-Response on the Chemopreventive Effects of Sarcophine-Diol on UVB-Induced Skin Tumor Development in SKH-1 Hairless Mice

Dose-Response on the Chemopreventive Effects of Sarcophine-Diol on UVB-Induced Skin Tumor Development in SKH-1 Hairless Mice

Sarcophine-diol (SD) is a lactone ring-opened analogue of sarcophine. It has shown chemopreventive effects on chemically-induced skin tumor development in female CD-1 mice, as well as in a UVB-induced skin tumor development model in hairless SKH-1 mice at a dose of 30 μg SD applied topically and 180...

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Bibliographic Details
Main Authors: Chandradhar Dwivedi, Sherief Khalifa, Hesham Fahmy, Xiaoying Zhang, Radhey S. Kaushik, David Zeman, Safwat A. Ahmed, Ruth F. Guillermo
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Marine Drugs
Subjects:
sarcophine-diol
skin cancer
chemopreventive agent
SKH-1 mice
UVB radiation
Online Access:http://www.mdpi.com/1660-3397/10/9/2111

Internet

http://www.mdpi.com/1660-3397/10/9/2111

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