Structure-based design of some quinazoline derivatives as epidermal growth factor receptor inhibitors

Structure-based design of some quinazoline derivatives as epidermal growth factor receptor inhibitors

Abstract Background The discovery of epidermal growth factor receptor (EGFR) inhibitors for the treatment of lung cancer, most especially non-small cell lung cancer (NSCLC), was one of the major challenges encountered by the medicinal chemist in the world. The treatment of EGFR tyrosine kinase to ma...

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Bibliographic Details
Main Authors: Muhammad Tukur Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Structure-based
Design
EGFR
Inhibitors
Pharmacokinetic
Prediction
Online Access:http://link.springer.com/article/10.1186/s43042-020-00107-y

Internet

http://link.springer.com/article/10.1186/s43042-020-00107-y

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