Inducible Genome Editing with Conditional CRISPR/Cas9 Mice

Genetically engineered mouse models (GEMMs) are powerful tools by which to probe gene function in vivo, obtain insight into disease etiology, and identify modifiers of drug response. Increased sophistication of GEMMs has led to the design of tissue-specific and inducible models in which genes of int...

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Bibliographic Details
Main Authors: Alexandra Katigbak, Francis Robert, Marilène Paquet, Jerry Pelletier
Format: Article
Language:English
Published: Oxford University Press 2018-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300327