Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development

Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development

Plasmodium parasites undergo a dramatic transformation during the liver stage of their life cycle, amplifying over 10,000-fold inside infected hepatocytes within a few days. Such a rapid growth requires large-scale interactions with, and manipulations of, host cell functions. Whereas hepatocyte pola...

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Bibliographic Details
Main Authors: Lakshmi Balasubramanian, Vanessa Zuzarte-Luís, Tabish Syed, Debakshi Mullick, Saptarathi Deb, Harish Ranga-Prasad, Jana Meissner, Ana Almeida, Tobias Furstenhaupt, Kaleem Siddiqi, Miguel Prudêncio, Cecilia M. P. Rodrigues, Maria Mota, Varadharajan Sundaramurthy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
plasmodium liver stage
hepatocyte polarity
ultrastructure
3D image analysis
liver tissue
bile canaliculi
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00451/full

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https://www.frontiersin.org/article/10.3389/fcimb.2019.00451/full

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