Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study

Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study

Human apoE exhibits three major isoforms (apoE2, apoE3, and apoE4) corresponding to polymorphism in the APOE gene. Total plasma apoE concentrations are closely related to these isoforms, but the underlying mechanisms are unknown. We aimed to describe the kinetics of apoE individual isoforms to explo...

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Bibliographic Details
Main Authors: Valentin Blanchard, Stéphane Ramin-Mangata, Stéphanie Billon-Crossouard, Audrey Aguesse, Manon Durand, Kevin Chemello, Brice Nativel, Laurent Flet, Maud Chétiveaux, David Jacobi, Jean-Marie Bard, Khadija Ouguerram, Gilles Lambert, Michel Krempf, Mikaël Croyal
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
peptide
liquid chromatography
tandem mass spectrometry
stable isotope tracers
lipoprotein/kinetics
lipoprotein/metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331242

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http://www.sciencedirect.com/science/article/pii/S0022227520331242

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