Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. Despite intensive treatment, the prognosis for patients with GBM remains grim with a median survival of only 14.6 months. Immunotherapy has emerged as a promising approach for treating many cancers and aff...

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Bibliographic Details
Main Authors: Christopher Jackson, Jacob Ruzevick, Jillian Phallen, Zineb Belcaid, Michael Lim
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2011/732413