Cynomolgus monkeys (Macaca fascicularis) experimentally and naturally infected with hepatitis E virus: The bone marrow as a possible new viral target.

Hepatitis E virus (HEV) transmission through infected blood and blood products has already been described. However, little is known about the bone marrow (BM) as source of HEV infection. Our study aimed to investigate the presence of HEV antigen (Ag) and histological changes in BM of cynomolgus monk...

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Bibliographic Details
Main Authors: Fernanda de Oliveira Bottino, Noemi Rovaris Gardinali, Sarah Beatriz Salamene Salvador, Andreza Soriano Figueiredo, Lynn Barwick Cysne, Juliane Siqueira Francisco, Jaqueline Mendes de Oliveira, Marcelo Pelajo Machado, Marcelo Alves Pinto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6168161?pdf=render