Molecular Features of Non-Selective Small Molecule Antagonists of the Bradykinin Receptors

Angiotensin converting enzyme 2 (ACE2) downregulation is a key negative factor for the severity of lung edema and acute lung failure observed in patients infected with SARS-CoV-2. ACE2 downregulation affects the levels of diverse peptide mediators of the renin-agiotensin-aldestosterone and kallikrei...

Full description

Bibliographic Details
Main Authors: Bahareh Rasaeifar, Patricia Gomez-Gutierrez, Juan J. Perez
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/9/259