Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function.

Neurodegenerative disorders are associated with impaired cognitive function and worse physical health outcomes. This study aims to test whether polygenic risk for Alzheimer's disease, Amyotrophic Lateral Sclerosis (ALS), or frontotemporal dementia (FTD) is associated with cognitive function and...

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Bibliographic Details
Main Authors: Saskia P Hagenaars, Ratko Radaković, Christopher Crockford, Chloe Fawns-Ritchie, International FTD-Genomics Consortium (IFGC), Sarah E Harris, Catharine R Gale, Ian J Deary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0198187