Identification and visualization of CD8+ T cell mediated IFN-γ signaling in target cells during an antiviral immune response in the brain.

Identification and visualization of CD8+ T cell mediated IFN-γ signaling in target cells during an antiviral immune response in the brain.

CD8(+) T cells infiltrate the brain during an anti-viral immune response. Within the brain CD8(+) T cells recognize cells expressing target antigens, become activated, and secrete IFNγ. However, there are no methods to recognize individual cells that respond to IFNγ. Using a model that studies the e...

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Bibliographic Details
Main Authors: Mariana Puntel, Robert Barrett, Nicholas S R Sanderson, Kurt M Kroeger, Niyati Bondale, Mia Wibowo, Sean Kennedy, Chunyan Liu, Maria G Castro, Pedro R Lowenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3163574?pdf=render

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http://europepmc.org/articles/PMC3163574?pdf=render

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