Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin

Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin

Abstract Background Respiratory syncytial virus (RSV) infects the central nervous system, resulting in neurological symptoms. However, the precise underlying pathogenic mechanisms have not been elucidated. In the present study, the infectivity of RSV on N2a neuronal cells and the possible roles of T...

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Bibliographic Details
Main Authors: Xiaoling Yuan, Tao Hu, Hanwen He, Huan Qiu, Xuan Wu, Jingxian Chen, Minmin Wang, Cheng Chen, Shenghai Huang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Biomedical Science
Subjects:
Respiratory syncytial virus (RSV)
Toll-like receptor 4 (TLR4)
Nucleolin (C23)
Virus infection
N2a cells
Online Access:http://link.springer.com/article/10.1186/s12929-018-0416-6

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http://link.springer.com/article/10.1186/s12929-018-0416-6

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