Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury

Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury

Abstract Background Malaria-triggered lung injury can occur in both severe and non-severe cases. Platelets may interact with parasitized erythrocytes, leukocytes and endothelium. These interactions can lead to microvessel obstructions and induce release of inflammatory mediators. Induction of the ha...

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Bibliographic Details
Main Authors: Isaclaudia G. de Azevedo-Quintanilha, Isabel M. Medeiros-de-Moraes, André C. Ferreira, Patrícia A. Reis, Adriana Vieira-de-Abreu, Robert A. Campbell, Andrew S. Weyrich, Patricia T. Bozza, Guy A. Zimmerman, Hugo C. Castro-Faria-Neto
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Malaria Journal
Subjects:
Acute lung injury
Acute respiratory distress syndrome
Inflammation
Malaria
Platelets
Heme oxygenase 1
Online Access:http://link.springer.com/article/10.1186/s12936-020-03305-6

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http://link.springer.com/article/10.1186/s12936-020-03305-6

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