Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing

Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing

DNA methyltransferases (MTases), which catalyze the methylation of adenine and cytosine bases in DNA, can occur in bacteria and archaea alongside cognate restriction endonucleases (REases) in restriction-modification (RM) systems or independently as orphan MTases. Although DNA methylation and MTases...

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Bibliographic Details
Main Authors: Matthew Ouellette, J. Peter Gogarten, Jessica Lajoie, Andrea M. Makkay, R. Thane Papke
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Genes
Subjects:
haloarchaea
Halobacteria
Haloferax volcanii
DNA methylation
methylation
methylome
restriction-modification system
CTAG methylation
GATC methylation
Online Access:http://www.mdpi.com/2073-4425/9/3/129

Internet

http://www.mdpi.com/2073-4425/9/3/129

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