RNA-activated protein kinase differentially modulates innate immune response mediated by supraphysiological concentrations of thyroid hormone
Nuclear hormone receptor ligands are known to modulate innate immunity by dampening the immune response induced by pathogens. Here, we report that unlike other ligands, 3,3′,5-triiodo- l -thyronine (T3) induced the type 1 IFN response and expression of IFN-stimulated genes (ISGs). T3 action was foun...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-11-01
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| Series: | Innate Immunity |
| Online Access: | https://doi.org/10.1177/1753425920955214 |