Anopheles gambiae PGRPLC-mediated defense against bacteria modulates infections with malaria parasites.

Recognition of peptidoglycan (PGN) is paramount for insect antibacterial defenses. In the fruit fly Drosophila melanogaster, the transmembrane PGN Recognition Protein LC (PGRP-LC) is a receptor of the Imd signaling pathway that is activated after infection with bacteria, mainly Gram-negative (Gram-)...

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Bibliographic Details
Main Authors: Stephan Meister, Bogos Agianian, Fanny Turlure, Angela Relógio, Isabelle Morlais, Fotis C Kafatos, George K Christophides
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19662170/?tool=EBI