High-Molecular-Weight Hyaluronic Acid Vehicle Can Deliver Gadolinium Into the Cochlea at a Higher Concentration for a Longer Duration: A 9.4-T Magnetic Resonance Imaging Study

High-Molecular-Weight Hyaluronic Acid Vehicle Can Deliver Gadolinium Into the Cochlea at a Higher Concentration for a Longer Duration: A 9.4-T Magnetic Resonance Imaging Study

Intratympanic (IT) gadolinium (Gd) injection is one method of delivering Gd into the inner ear to evaluate the amount of endolymphatic hydrops (EH) using magnetic resonance imaging (MRI). As Gd is usually prepared in a fluid form mixed with saline, Gd injected into the middle ear drains easily throu...

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Bibliographic Details
Main Authors: Yu-Jung Hwang, Mina Park, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Myung-Whan Suh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neurology
Subjects:
magnetic resonance imaging
hyaluronic acid
gadolinium
drug delivery
cochlea
intratympanic injection
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.650884/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.650884/full

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