Complex versus simple models: ion-channel cardiac toxicity prediction

There is growing interest in applying detailed mathematical models of the heart for ion-channel related cardiac toxicity prediction. However, a debate as to whether such complex models are required exists. Here an assessment in the predictive performance between two established large-scale biophysic...

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Bibliographic Details
Main Author: Hitesh B. Mistry
Format: Article
Language:English
Published: PeerJ Inc. 2018-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4352.pdf