Human and mouse CD8+CD25+FOXP3+ regulatory T cells at steady state and during interleukin-2 therapy

In addition to CD4+ regulatory T cells (Tregs), CD8+ suppressor T cells are emerging as an important subset of regulatory T cells. Diverse populations of CD8+ T cells with suppressive activities have been described. Among them, a small population of CD8+CD25+FOXP3+ T cells is found both in mice and...

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Bibliographic Details
Main Authors: Guillaume eChurlaud, fabien epitoiset, fadi ejebbawi, roberta elorenzon, bertrand ebellier, michelle erosenzwajg, David eKlatzmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00171/full