The emerging roles of IDO2 in cancer and its potential as a therapeutic target

During the past decades, tryptophan metabolism disorder was discovered to play a vital and complex role in the development of cancer. Indoleamine 2,3-dioxygenase 2 (IDO2) is one of the initial and rate-limiting enzymes of the kynurenine pathway of tryptophan catabolism. Increasing evidence indicates...

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Bibliographic Details
Main Authors: Pengcheng Li, Weiqi Xu, Furong Liu, He Zhu, Lu Zhang, Zeyang Ding, Huifang Liang, Jia Song
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221000809