Endoplasmic reticulum stress, unfolded protein response and altered T cell differentiation in necrotizing enterocolitis.

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) play important roles in chronic intestinal inflammation. Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in preterm infants and is characterized by acute intestinal inflammation and...

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Bibliographic Details
Main Authors: Peng Lu, Marie-Chantal Struijs, Jiaping Mei, Janneke Witte-Bouma, Anita M Korteland-van Male, Adrianus C J M de Bruijn, Johannes B van Goudoever, Ingrid B Renes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806824?pdf=render