Quantitative control of noise in mammalian gene expression by dynamic histone regulation

Fluctuation ('noise') in gene expression is critical for mammalian cellular processes. Numerous mechanisms contribute to its origins, yet the mechanisms behind large fluctuations that are induced by single transcriptional activators remain elusive. Here, we probed putative mechanisms by st...

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Bibliographic Details
Main Authors: Deng Tan, Rui Chen, Yuejian Mo, Shu Gu, Jiao Ma, Wei Xu, Xibin Lu, Huiyu He, Fan Jiang, Weimin Fan, Yili Wang, Xi Chen, Wei Huang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/65654

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