Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine

Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine

Abstract Background MicroRNA-29c (miR-29c) is abnormally expressed in several cancers and serves as an important predictor of tumor prognosis. Herein, we investigate the effects of abnormal miR-29c expression and analyze its clinical significance in acute myeloid leukemia (AML) patients. In addition...

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Bibliographic Details
Main Authors: Li-juan Tang, Guo-kang Sun, Ting-juan Zhang, De-hong Wu, Jing-dong Zhou, Bei-bei Ma, Zi-jun Xu, Xiang-mei Wen, Qin Chen, Dong-ming Yao, Jun Qian, Ji-chun Ma, Jiang Lin
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cancer Cell International
Subjects:
MiR-29c expression
Acute myeloid leukemia
Prognostic
Decitabine
Online Access:http://link.springer.com/article/10.1186/s12935-019-0894-y

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http://link.springer.com/article/10.1186/s12935-019-0894-y

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