Distinct Signaling Pathways Between Human Macrophages and Primary Gingival Epithelial Cells by <i>Aggregatibacter actinomycetemcomitans</i>

In aggressive periodontitis, the dysbiotic microbial community in the subgingival crevice, which is abundant in Aggregatibacter actinomycetemcomitans, interacts with extra- and intracellular receptors of host cells, leading to exacerbated inflammation and subsequent tissue destruction. Our goal was...

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Bibliographic Details
Main Authors: Ellen S. Ando-Suguimoto, Manjunatha R. Benakanakere, Marcia P.A. Mayer, Denis F. Kinane
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/4/248