Determination of imatinib intracellular uptake in leukocytes as a prognostic factor in cML therapy
Background: Imatinib is the first target therapy for chronic myelogenous leukemia (CML). Response to imatinib treatment also depends on the uptake of the drug into the target cell by organic cation transporter 1 (OCT1). OCT1 activity determined by the uptake of 14C-imatinib (IUR) in isolated mon...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2012-12-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/757 |