Circulating Retinol-Binding Protein 4 as a Possible Biomarker of Treatment Response for Ankylosing Spondylitis: An Array-Based Comparative Study

Circulating Retinol-Binding Protein 4 as a Possible Biomarker of Treatment Response for Ankylosing Spondylitis: An Array-Based Comparative Study

ObjectiveTo explore proteins associated with ankylosing spondylitis (AS) and to investigate potential proteins that may predict treatment response of adalimumab (ADA) in AS patients.MethodsIn the discovery cohort, 39 AS patients and 20 healthy controls (HCs) were included, and 16 AS patients receive...

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Bibliographic Details
Main Authors: Jialing Wu, Xinyu Wu, Zena Chen, Qing Lv, Mingcan Yang, Xuqi Zheng, Qiuxia Li, Yanli Zhang, Qiujing Wei, Shuangyan Cao, Xiaomin Li, Jun Qi, Minjing Zhao, Zetao Liao, Zhiming Lin, Jieruo Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
ankylosing spondylitis
adalimumab
protein arrays
retinol-binding protein 4
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00231/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00231/full

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