Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-α-Induced Apoptosis

Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-α-Induced Apoptosis

Background/Aims: Both physiologic remodeling and pathologic regeneration of cartilage tissue rely upon chondrocyte functions and are benefited from factors that promote viability and inhibit apoptosis of the cell, and associated mechanisms. High level of reactive oxygen species (ROS) and proinflamma...

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Bibliographic Details
Main Authors: Siming Li, Xiaohong Yang, Zhencheng Feng, Pengzhen Wang, Weicong Zhu, Shuliang Cui
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Catalase (CAT)
Antioxidant
Tumor necrosis factor-α (TNF-α)
Death cascade
Anti-apoptosis
Cell viability
C28/I2 chondrocytes
Online Access:https://www.karger.com/Article/FullText/493841

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https://www.karger.com/Article/FullText/493841

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