Analysis of herpes simplex virion tegument ICP4 derived from infected cells and ICP4-expressing cells.

ICP4 is the major transcriptional regulatory protein of herpes simplex virus (HSV). It is expressed in infected cells with immediate early kinetics and is essential for viral growth. ICP4 is also a structural component of the virion tegument layer. Herpesviral tegument proteins exert regulatory func...

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Bibliographic Details
Main Authors: Suzanne M Pritchard, Cristina W Cunha, Anthony V Nicola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3735503?pdf=render