Regulation of Endoplasmic Reticulum–Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies

Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute intracellular Ca2+ among several compartments. The re...

Full description

Bibliographic Details
Main Authors: Gaia Pedriali, Alessandro Rimessi, Luigi Sbano, Carlotta Giorgi, Mariusz R. Wieckowski, Maurizio Previati, Paolo Pinton
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Oncology
Subjects:
ROS
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00180/full