Effect of p53 activation on experimental right ventricular hypertrophy.

The leading cause of death in Pulmonary Arterial Hypertension (PAH) is right ventricular (RV) failure. The tumor suppressor p53 has been associated with left ventricular hypertrophy (LVH) and remodeling but its role in RV hypertrophy (RVH) is unclear. The purpose of this study was to determine wheth...

Full description

Bibliographic Details
Main Authors: Swathi Veeroju, Argen Mamazhakypov, Nabham Rai, Baktybek Kojonazarov, Valerie Nadeau, Sandra Breuils-Bonnet, Ling Li, Norbert Weissmann, Susanne Rohrbach, Steve Provencher, Sébastien Bonnet, Werner Seeger, Ralph Schermuly, Tatyana Novoyatleva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234872