Platycodin D Blocks Breast Cancer-Induced Bone Destruction by Inhibiting Osteoclastogenesis and the Growth of Breast Cancer Cells

Platycodin D Blocks Breast Cancer-Induced Bone Destruction by Inhibiting Osteoclastogenesis and the Growth of Breast Cancer Cells

Background: Metastatic breast cancer cells are frequently associated with osteoclast-mediated bone resorption, resulting in severe bone destruction and increased mortality in patients. Platycodin D (PD) isolated from Platycodon grandiflorum is a triterpenoid saponin with anti-cancer and anti-angioge...

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Bibliographic Details
Main Authors: Sun Kyoung Lee, Kwang-Kyun Park, Hyun-Jeong Kim, Ki Rim Kim, Eun Ji Kang, Yu Li Kim, Heein Yoon, Yeong Shik Kim, Won-Yoon Chung
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Breast cancer
Bone destruction
Platycodin D
Osteoclastogenesis
Online Access:http://www.karger.com/Article/FullText/430152

Internet

http://www.karger.com/Article/FullText/430152

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