Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis.

Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis.

Inclusion body myositis (IBM) belongs to a group of muscle diseases known as the inflammatory myopathies. The presence of antibody-secreting plasma cells in IBM muscle implicates the humoral immune response in this disease. However, whether the humoral immune response actively contributes to IBM pat...

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Bibliographic Details
Main Authors: Arundhati Ray, Anthony A Amato, Elizabeth M Bradshaw, Kevin J Felice, Daniel B DiCapua, Jonathan M Goldstein, Ingrid E Lundberg, Richard J Nowak, Hidde L Ploegh, Eric Spooner, Qian Wu, Simon N Willis, Kevin C O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3465259?pdf=render

Internet

http://europepmc.org/articles/PMC3465259?pdf=render

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