Purines and Carotid Body: New Roles in Pathological Conditions

It is known that adenosine and adenosine-5′-triphosphate (ATP) are excitatory mediators involved in carotid body (CB) hypoxic signaling. The CBs are peripheral chemoreceptors classically defined by O2, CO2, and pH sensors. When hypoxia activates the CB, it induces the release of neurotransmitters fr...

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Bibliographic Details
Main Authors: Silvia V. Conde, Emilia C. Monteiro, Joana F. Sacramento
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pharmacology
Subjects:
ATP
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00913/full