Systematic Investigation of DNA Methylation Associated With Platinum Chemotherapy Resistance Across 13 Cancer Types

Background: Platinum resistance poses a significant problem for oncology clinicians. As a result, the role of epigenetics and DNA methylation in platinum-based chemoresistance has gained increasing attention from researchers in recent years. A systematic investigation of aberrant methylation pattern...

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Bibliographic Details
Main Authors: Ruizheng Sun, Chao Du, Jiaxin Li, Yanhong Zhou, Wei Xiong, Juanjuan Xiang, Jiheng Liu, Zhigang Xiao, Li Fang, Zheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
DNA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.616529/full