Mucosal Therapy of Multi-Drug Resistant Tuberculosis With IgA and Interferon-γ

Mucosal Therapy of Multi-Drug Resistant Tuberculosis With IgA and Interferon-γ

New evidence has been emerging that antibodies can be protective in various experimental models of tuberculosis. Here, we report on protection against multidrug-resistant Mycobacterium tuberculosis (MDR-TB) infection using a combination of the human monoclonal IgA 2E9 antibody against the alpha-crys...

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Bibliographic Details
Main Authors: Andy C. Tran, Gil R. Diogo, Matthew J. Paul, Alastair Copland, Peter Hart, Nickita Mehta, Edward. B. Irvine, Tufária Mussá, Pascal M. W. Drake, Juraj Ivanyi, Galit Alter, Rajko Reljic
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
IgA
mAb—monoclonal antibody
drug resistance
HspX
alpha crystallin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.582833/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.582833/full

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