Cullin3-BTB interface: a novel target for stapled peptides.

Cullin3-BTB interface: a novel target for stapled peptides.

Cullin3 (Cul3), a key factor of protein ubiquitination, is able to interact with dozens of different proteins containing a BTB (Bric-a-brac, Tramtrack and Broad Complex) domain. We here targeted the Cul3-BTB interface by using the intriguing approach of stabilizing the α-helical conformation of Cul3...

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Bibliographic Details
Main Authors: Ivan de Paola, Luciano Pirone, Maddalena Palmieri, Nicole Balasco, Luciana Esposito, Luigi Russo, Daniela Mazzà, Lucia Di Marcotullio, Sonia Di Gaetano, Gaetano Malgieri, Luigi Vitagliano, Emilia Pedone, Laura Zaccaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388676?pdf=render

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http://europepmc.org/articles/PMC4388676?pdf=render

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