The role of CDK in the initiation step of DNA replication in eukaryotes

<p>Abstract</p> <p>Cyclin-dependent kinases (CDKs) regulate the progression of the cell cycle in eukaryotes. One of the major roles of CDK is to promote chromosomal DNA replication. However, how CDKs promote DNA replication has been a long-standing question, because all the essenti...

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Bibliographic Details
Main Authors: Tak Yon-Soo, Tanaka Seiji, Araki Hiroyuki
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/2/1/16