Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats

Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats

The objective of this investigation was to study whether Nigella Sativa and Trigonella Foenum-graecum, could modulate the losartan pharmacodynamic (PD) and pharmacokinetic (PK) in experimental L-NAME induced hypertensive rats. For in vivo study, the systolic blood pressure (SBP) of rats was measured...

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Bibliographic Details
Main Authors: Abdul Ahad, Mohammad Raish, Yousef A. Bin Jardan, Mohd Aftab Alam, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Saudi Journal of Biological Sciences
Subjects:
L-NAME
Losartan
Nigella Sativa
Pharmacodynamic
Pharmacokinetic
Trigonella Foenum-graecum
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20301819

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http://www.sciencedirect.com/science/article/pii/S1319562X20301819

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