Excretion of the Polymyxin Derivative NAB739 in Murine Urine

Extremely multiresistant strains of Enterobacteriaceae are emerging and spreading at a worrisome pace. Polymyxins are used as the last-resort therapy against such strains, in spite of their nephrotoxicity. We have previously shown that novel polymyxin derivatives NAB739 and NAB815 are less nephrotox...

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Bibliographic Details
Main Authors: Martti Vaara, Timo Vaara, Janis Kuka, Eduards Sevostjanovs, Solveiga Grinberga, Maija Dambrova, Edgars Liepinsh
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/9/4/143