Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 Levels

Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 Levels

Chemoresistance is a major problem in the therapeutic management of pancreatic cancer, concurring to poor clinical outcome. A number of mechanisms have been proposed to explain resistance to gemcitabine, a standard of care for this malignancy, among which is included aberrant miRNA expression. In th...

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Bibliographic Details
Main Authors: Concetta Panebianco, Nadia Trivieri, Annacandida Villani, Fulvia Terracciano, Tiziana Pia Latiano, Adele Potenza, Francesco Perri, Elena Binda, Valerio Pazienza
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
miRNA
pancreatic cancer
chemoresistance
Online Access:https://www.mdpi.com/2218-273X/11/5/639

Internet

https://www.mdpi.com/2218-273X/11/5/639

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