In Vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-length (YAC128) Transgenic Mouse Models of Huntington’s Disease
Huntington’s disease (HD) is characterized by alterations within the corticostriatal circuitry. The striatum is innervated by a dense array of dopaminergic (DA) terminals and these DA synapses are critical to the proper execution of motor functions. As motor disturbances are prevalent in HD we exami...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2011-07-01
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| Series: | Frontiers in Systems Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00061/full |