Aerosol vaccination with Bacille Calmette-Guerin induces a trained innate immune phenotype in calves.

Mycobacterium bovis Bacillus Calmette-Guérin (BCG) is a live attenuated vaccine for use against tuberculosis (TB); however, it is known to reduce childhood mortality from infections other than TB. The unspecific protection induced by BCG vaccination has been associated with the induction of memory-l...

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Bibliographic Details
Main Authors: Mariana Guerra-Maupome, Dua X Vang, Jodi L McGill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212751