High follicle‐stimulating hormone levels accelerate cartilage damage of knee osteoarthritis in postmenopausal women through the PI3K/AKT/NF‐κB pathway

High follicle‐stimulating hormone levels accelerate cartilage damage of knee osteoarthritis in postmenopausal women through the PI3K/AKT/NF‐κB pathway

Osteoarthritis is the main cause of pain and disability in the elderly, with the most commonly affected joint being the knee. The prevalence of knee osteoarthritis (KOA) is significantly increased in postmenopausal women, although the mechanisms underlying KOA remain unclear. The present study aimed...

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Bibliographic Details
Main Authors: Yaping Liu, Mengqi Zhang, Dehuan Kong, Yan Wang, Jian Li, Wenjuan Liu, Yilin Fu, Jin Xu
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:FEBS Open Bio
Subjects:
aggrecan
follicle‐stimulating hormone
knee osteoarthritis
PI3K/AKT/NF‐κB pathway
postmenopausal women
type II collagen
Online Access:https://doi.org/10.1002/2211-5463.12975

Internet

https://doi.org/10.1002/2211-5463.12975

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