Vitamin D Binding Protein-Macrophage Activating Factor (DBP-maf) Inhibits Angiogenesis and Tumor Growth in Mice

We have isolated a selectively deglycosylated form of vitamin D binding protein (DBP-maf) generated from systemically available DBP by a human pancreatic cancer cell line. DBP-maf is anti proliferative for endothelial cells and antiangiogenic in the chorioallantoic membrane assay. DBP-maf administe...

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Bibliographic Details
Main Authors: Oliver Kisker, Shinya Onizuka, Christian M. Becker, Michael Fannon, Evelyn Flynn, Robert D'Amato, Bruce Zetter, Judah Folkman, Rahul Ray, Narasimha Swamy, Steven Pirie-Shepherd
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558603800155