Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.

Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.

Visceral leishmaniasis (VL) is a neglected tropical disease and is fatal if untreated. There is no vaccine available against leishmaniasis. The majority of patients with cutaneous leishmaniasis (CL) or VL develop a long-term protective immunity after cure from infection, which indicates that develop...

Full description

Bibliographic Details
Main Authors: Jacqueline Araújo Fiuza, Ranadhir Dey, Dwann Davenport, Maha Abdeladhim, Claudio Meneses, Fabiano Oliveira, Shaden Kamhawi, Jesus G Valenzuela, Sreenivas Gannavaram, Hira L Nakhasi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4708988?pdf=render

Internet

http://europepmc.org/articles/PMC4708988?pdf=render

Similar Items