Iron Metabolism: An Under Investigated Driver of Renal Pathology in Lupus Nephritis

Nephritis is a common manifestation of systemic lupus erythematosus, a condition associated with inflammation and iron imbalance. Renal tubules are the work horse of the nephron. They contain a large number of mitochondria that require iron for oxidative phosphorylation, and a tight control of intra...

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Bibliographic Details
Main Authors: Ewa Wlazlo, Borna Mehrad, Laurence Morel, Yogesh Scindia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
SLE
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.643686/full