Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter

Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter

Long-chain fatty acids activate the free fatty acid receptor 1 (FFA1) and FFA4. In the gastrointestinal system, FFA1 and FFA4 have been found in the pancreas and intestine. Fatty food and decreased lower esophageal sphincter (LES) motility are associated with gastroesophageal reflux disease. The eff...

Full description

Bibliographic Details
Main Authors: Ching-Chung Tsai, Yi-Chen Li, Li-Ching Chang, Shu-Leei Tey, Kai-Jen Lin, Shih-Che Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
motility
lower esophageal sphincter
free fatty acid receptor
FFA1
FFA4
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00676/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00676/full

Similar Items