An Update on the Role of Leptin in the Immuno-Metabolism of Cartilage

An Update on the Role of Leptin in the Immuno-Metabolism of Cartilage

Since its discovery in 1994, leptin has been considered as an adipokine with pleiotropic effects. In this review, we summarize the actual information about the impact of this hormone on cartilage metabolism and pathology. Leptin signalling depends on the interaction with leptin receptor LEPR, being...

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Bibliographic Details
Main Authors: Alfonso Cordero-Barreal, María González-Rodríguez, Clara Ruiz-Fernández, Djedjiga Ait Eldjoudi, Yousof Ramadan Farrag AbdElHafez, Francisca Lago, Javier Conde, Rodolfo Gómez, Miguel Angel González-Gay, Ali Mobasheri, Jesus Pino, Oreste Gualillo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
leptin
articular cartilage
chondrocyte
LEPR (ObR), osteoarthritis (OA)
rheumatoid arthritis (RA)
Online Access:https://www.mdpi.com/1422-0067/22/5/2411

Internet

https://www.mdpi.com/1422-0067/22/5/2411

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