Altered thymic function during interferon therapy in HCV-infected patients.

Interferon alpha (IFNα) therapy, despite good efficacy in curing HCV infection, leads to major side effects, in particular inducement of a strong peripheral T-cell lymphocytopenia. We here analyze the early consequences of IFNα therapy on both thymic function and peripheral T-cell homeostasis in pat...

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Bibliographic Details
Main Authors: Stephanie Beq, Sandra Rozlan, Sandy Pelletier, Bernard Willems, Julie Bruneau, Jean-Daniel Lelievre, Yves Levy, Naglaa H Shoukry, Rémi Cheynier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3328332?pdf=render