Modification of TRPV4 activity by acetaminophen

Modification of TRPV4 activity by acetaminophen

N-Acetyl-p-aminophenol (APAP/acetaminophen) is a widely used analgesic/antipyretic with weaker inhibitory effects on cyclooxygenase compared to those of non-steroidal anti-inflammatory drugs. The effect of APAP is mediated by its metabolites, N-arachidonoyl-phenolamine and N-acetyl-p-benzoquinone im...

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Bibliographic Details
Main Authors: Fumio Nakagawa, Sen Higashi, Eika Ando, Tomoko Ohsumi, Seiji Watanabe, Hiroshi Takeuchi
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Heliyon
Subjects:
Electrophysiology
Molecular neuroscience
Cell culture
Membrane
Physiology
Nervous system
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020301468

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http://www.sciencedirect.com/science/article/pii/S2405844020301468

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