Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Summary: Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may occur in response to LIF-STAT3 signaling; however, l...

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Bibliographic Details
Main Authors: Hideyuki Murayama, Hideki Masaki, Hideyuki Sato, Tomonari Hayama, Tomoyuki Yamaguchi, Hiromitsu Nakauchi
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003609

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http://www.sciencedirect.com/science/article/pii/S2213671114003609

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